DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

Over a hundred sickle cell warriors and their families turned out in support for World Sickle Cell Day at West Oakland’s ...

Some doctors told him he'd live with the disease forever, but Khaled Alsheebani never stopped believing treatments would advance one day.

The condition mostly affects those from African and Caribbean backgrounds but Victoria Ekanoye says it can affect anyone. | ...

Rising sickle cell disease in children demands urgent awareness. Early diagnosis, modern therapies, and vigilant care can ...

Sickle cell disease arises from a single genetic mutation in the gene that produces the β-globin part of haemoglobin. This mutation creates an abnormal form of haemoglobin called haemoglobin S.

Even if these treatments were more widely available, they would not eliminate the sickle cell mutation from reproductive DNA—thus perpetuating the genetic transmission to future generations.

On Juneteenth, UAMS in Little Rock held an event aimed at highlighting Sickle Cell Disease, which is a disease most common in people of African American descent.

Sickle cell disease articles from across Nature Portfolio Sickle cell disease is an autosomal recessive blood disorder that can lead to anaemia. It is caused by a mutation in the haemoglobin gene ...

These other forms of sickle-cell disease are compound heterozygous states in which the person has only one copy of the mutation that causes HbS and one copy of another abnormal haemoglobin allele.

The gene-editing platform known as Crispr is widely used by researchers in scientific laboratories in their search for new ...