Doctors noticed that patients who had sickle cell anemia, a serious hereditary blood disease, were more likely to survive malaria, a disease which kills some 1.2 million people every year.

Can we predict that natural selection will weed out genetic disease over time? Sickle-cell trait haplotype distribution shows the genetic advantages of this mutation. In the deoxygenated ...

On this map, the distribution of sickle-cell anemia haplotypes among nations with high prevalence of the disease are shown. Five distinct beta-globin haplotypes (indicated by colors) are found in ...

In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...

Simmie White is taking control of her own story. The six-year-old girl and her mother want others to understand more about ...

Hydroxyurea Significantly Reduces Infections in Children With Sickle Cell Anemia Jan. 29, 2024 — Researchers have revealed that hydroxyurea significantly reduces infections in children with ...

The UAB Comprehensive Sickle Cell Center brings together scholars and researchers working in the forefront of basic, translational and clinical research, with the overarching goals to discover new ...

The Medical University of South Carolina Health has established the Rena N. Grant Sickle Cell Center to help treat those ...

Kyle Registre's childhood dream of becoming a pilot can finally come true now that he says he's been cured of sickle cell ...

By Balambal Suryanarayanan CRISPR-Cas9 is a repurposed gene editing tool that allows scientists to cut, replace, and insert pieces of DNA in precise regions along the strand. Courtesy of NIH Image ...

Children with sickle cell disease, a chronic hemolytic anemia, present with a wide variety of neurological syndromes, including ischemic and hemorrhagic stroke, transient ischemic attacks ...