Considéré comme une découverte révolutionnaire, l’outil d’édition du génome Crispr-Cas9 fait l’objet d’un bras de fer judiciaire depuis une décennie. Aux Etats-Unis, un tribunal a demandé un réexamen ...

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 gene-editing tool to spiders. Following the genetic modification, the spiders ...

The emergence of CRISPR-Cas9 genome-editing tools created new opportunities for enhancing plant and crop traits in agricultural biotechnology research. Now, multiplex genome-editing (MGE) technologies ...

Le complexe Crispr-Cas9 tient ici le rôle de la fonction "Rechercher" d'un traitement de texte, soit pour supprimer ensuite le mot, soit pour le remplacer par un autre. Crispr-Cas9 permet de supp ...

For a decade, leading academic institutes and their associated companies fought a bruising, headline-grabbing fight over who held patent rights to CRISPR-Cas9, the revolutionary genome editing tool.

Subsequently, DNA repair pathways like non-homologous end joining (NHEJ) or homology-directed repair bring the Cas9 and sgRNA together to ultimately modify the genome. The incorporation of CRISPR ...

The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 ...

L'histoire de l’outil révolutionnaire d’édition du génome ­CRISPR-Cas9 remonte aux années 1980, lorsqu’une équipe japonaise découvre qu’une région du chromosome de la bactérie ...

Whilst genome editing with CRISPR-Cas9 is effective, it runs the risk of off-target effects and excessive mutations, which can lead to toxicity. To reduce the likelihood of these occurring, ...

CRISPR-Cas9 gene editing technology is widely used to to help study genes of interest and modify disease-associated genes. However, the system is associated with adverse effects, including ...

A new class of spherical nucleic acids has been developed to deliver CRISPR-Cas9 machinery across cell membranes and into the nucleus, without the need for transfection agents. A research group led by ...