This interplay between CMA-driven protein targeting and macroautophagy-mediated vesicle dynamics provides a novel mechanistic framework for the unconventional secretion of PARK7." ...

Regulated secretion of neurotransmitters and neurohumoral factors from dense core secretory vesicles provides essential neuroeffectors for cell−cell communication in the nervous and endocrine systems.

The release of peptide hormones or neurotransmitters from neuroendocrine cells is essential for the co-ordination of diverse physiological events. Secretory vesicles derived from the trans-Golgi ...

Most of the components in the yeast secretory pathway have been studied, yet a high-resolution temporal timeline of their participation is lacking. Here, we define the order of acquisition, lifetime, ...

Secretory vesicles are then transported towards the plasma membrane where they finally fuse (Burgess and Kelly, 1987; Benham, 2012; Viotti, 2016). Thul et al., in 2017 published a subcellular map of ...

Scientists from The Hong Kong University of Science and Technology (HKUST) and The Hong Kong Polytechnic University (PolyU) have developed an in-vitro vesicle formation assay, shedding light on ...

3. Driedonks TAP, Nolte-’t Hoen ENM. Circulating Y-RNAs in extracellular vesicles and ribonucleoprotein complexes: implications for the immune system. Front Immunol 2019;9:3164-3164.

Intracellular transport relies on multiple kinesins, but it is poorly understood which kinesins are present on particular cargos, what their contributions are and whether they act simultaneously on ...

In this work, open carbon nanopipettes (CNPs) with radius between 50 and 600 nm were used to control translocation of different-sized vesicles through the pipette orifice followed by ...

Secretory vesicles play an important role in moving molecules outside of the cell, through a process called exocytosis. They are crucial for healthy organ and tissue function.

"Insulin release is controlled by the amount of Epac2A at the secretory vesicles." ScienceDaily. ScienceDaily, 7 July 2017. <www.sciencedaily.com / releases / 2017 / 07 / 170707133831.htm>.

Using advanced microscopy techniques, the researchers have now discovered that cyclic AMP triggers movement of Epac2A to the sites at the cell membrane where insulin vesicles are prepared for ...