As the most abundant class of antibodies found in the intestinal lumen of humans and in most other mammals, secretory IgA (SIgA) has long been recognized as a first line of defense in protecting ...

[16] Breast milk contains high concentration of secretory antibodies, mainly IgA, with a broad range of specificities reflecting both maternal immunologic memory and antigenic stimulation of ...

New research from the University of Cincinnati demonstrates how specially engineered bacteria taken orally can operate as a ...

IgA can be selectively exported to external secretions as secretory IgA (SIgA). The induction of SIgA serves as the first line of defense in protecting the mucosal surfaces from enteric toxins and ...

This funding will accelerate the advancement of Lactiga’s lead asset, LCTG-001—the first-ever secretory IgA (sIgA) mucosally-targeted replacement therapy for patients with compromised immune ...

“Non-secretory myeloma is not necessarily a separate disease ... blood tests to monitor levels of a protein — in her case, immunoglobulin A lambda (IgA) — secreted into her blood by myeloma cells.

A key component of this system is an antibody called secretory IgA. These antibodies latch on to bacteria to prevent them from invading the lungs. Secretory IgA doesn’t directly kill microbes ...

Upper respiratory tract infection (URTI) is a common illness. Recent studies have shown that suppression of secretory immunoglobulin A (SIgA) is associated with increased incidence of URTI. Objective: ...

Reflecting maternal environmental exposition and in virtue of its multiple mechanism of action, secretory IgA in milk exerts a decisive role in direct and cross-protection against a variety of ...