while Sanger sequencing still had its uses, the action had already moved elsewhere. The Broad had recently eliminated a number of its Sanger machines, and the remainder weren't even active on the ...

The Human Genome project set out to sequence all of the 3 billion nucleotides in the human genome. Exactly how was this daunting task done with such incredible speed and accuracy? In 1986, a ...

The primary practical difference between Sanger sequencing and next generation sequencing is the yield of sequence data. Illumina’s sequencing machine can produce up to 20 mega bases (Mb ...

In the late 1980s, automated Sanger sequencing machines could sequence approximately 1,000 bases per day. With continuous methodological advances and computational developments occurring in ...