Figure 1: Structure and motility models of KIF5 and KIF1A. The kinesin motor domain is composed of a single globular catalytic core and a short strand 'neck linker'. The catalytic core contains ...

The cytoskeleton is a network of filamentous and tubular protein structures that support cell shape, intracellular compartmentalisation and trafficking, cell migration and cell division.

The neurotropic Sindbis virus vector system was used to investigate a role for the survival motor neuron (SMN) protein in regulating neuronal apoptosis. Here we show that SMN protects primary neurons ...