Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But ...

Researchers have reported that they are the first to observe the dynamic, ratchet-like movements of single ribosomal molecules in the act of building proteins from genetic blueprints. The study ...

Researchers have captured elusive nanoscale movements of ribosomes at work, shedding light on how these cellular factories take in genetic instructions and amino acids to churn out proteins. The ...

Using single molecule fluorescence resonance energy transfer it is now possible to follow the intersubunit conformation of the ribosome, in real time, as it moves from one codon to the next. The ...

Reverse tRNA–mRNA movement on the ribosome. Reverse translocation was studied with post-translocation complexes, which were formed by adding EF-G and GTP to a pre-translocation complex ...

By analysing the rate of ribosome movement in yeast cells, a team from the University of Geneva (UNIGE), Switzerland, in collaboration with the University of Hamburg, has succeeded in demonstrating ...

Although decoding is globally analogous in both species, the reaction coordinate of aminoacyl-tRNA movement is altered on the human ribosome and the process is an order of magnitude slower.

By analysing the rate of ribosome movement in yeast cells, a team from the University of Geneva (UNIGE), Switzerland, in collaboration with the University of Hamburg, ...

Huntington’s disease (HD) is a progressive brain disorder caused by a mutated gene. This disease causes changes in the central area of the brain, which affects movement, mood, and cognition.

UC Berkeley researchers have captured elusive nanoscale movements of ribosomes at work, shedding light on how these cellular factories take in genetic instructions and amino acids to churn out ...