With a new mapping tool, Princeton engineers have revealed how a factory inside cells builds ribosomes, the machinery ...

In summary, these results identify DDX6 as a crucial regulator of mRNA translation and decay triggered by slow ribosome movement and provide insights into the mechanism by which DDX6 destabilizes ...

The rate of ribosome movement is sequence dependent and controlled by codon usage patterns (Gardin et al., 2014), mRNA secondary structure (Tuller et al., 2011), the charge of the nascent chain within ...

Although decoding is globally analogous in both species, the reaction coordinate of aminoacyl-tRNA movement is altered on the human ribosome and the process is an order of magnitude slower.

Humans vs. Bacteria: Differences in ribosome decoding revealed Date: April 5, 2023 Source: St. Jude Children's Research Hospital Summary: Scientists have found that human ribosomes decode mRNA ...

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona have discovered a mechanism involving ribosomes which helps the heart toggle between a 'regular maintenance mode' for day-to-day ...

Drawing on a range of examples, she explores what social movements have shown about the nature of justice, along with what it takes to create space for justice in the world. Moody-Adams considers ...

A speed regulated by the genetic code Thus, Not factors associate with the ribosome at precise moments during protein synthesis, to slow down the ribosome during translation by condensing the RNA and ...

By analysing the rate of ribosome movement in yeast cells, a team from the University of Geneva (UNIGE), Switzerland, in collaboration with the University of Hamburg, has succeeded in ...