Activation of TREM2 reduces TNF (tumor necrosis factor) in retina/retinal pigment epithelium/choroid complex ... with TREM2 KO mice with specific Cre drivers such as LysM, CD11b, or CX3CR1 Cre to ...

Retinal regeneration and visual recovery in a retinitis pigmentosa model mouse through administration of AAV2-Anti-PROX1 gene therapy. We demonstrate that after administration of adeno-associated ...

Products are independently selected by our editors. We may earn an affiliate commission from links. They always say, the best retinol serum is one you’ll actually use. (That’s actually the ...

A new study suggests that never-seen-before stem cells in the human retina can restore vision in mice with a common eye disorder. But more work is needed to translate the treatment to people.

This study presents valuable findings on the control of survival and maintenance of a specific set of brain resident immune cells. The authors generate a new animal model to enable sophisticated ...

The discovery of the role of autoimmunity in glaucoma and retinal ganglionic cell (RGC) death has led to a paradigm shift in our understanding of the etiopathology of glaucoma. Glaucoma can cause ...

Microglia are the predominant immune response cells and professional phagocytes of the central nervous system (CNS) that have been shown to be important for brain development and homeostasis. These ...

The microbially produced amino acid–derived metabolite imidazole propionate (ImP) contributes to the pathogenesis of type 2 diabetes. However, the effects of ImP on endothelial cell (EC) physiology ...

Posterior vitreous detachment (PVD) occurs when the vitreous—a gel-like fluid in the eye—detaches from the retina. This results in eye floaters and flashes of light that can be annoying but is usually ...