Proteomic studies revealed that mitochondria contain ∼1,000 (in yeast) to 1,500 (in humans) different proteins and led to the recent identification of new mitochondrial import pathways and ...

Mitochondria are organelles with two well-defined compartments: the matrix, surrounded by the inner membrane (IM), and the intermembrane space, surrounded by the outer membrane (OM). The IM is ...

Given that the role of PRMT1 in metabolic regulation has been well-documented, we then investigated whether PRMT1 is involved in transforming 6133 cells through metabolic reprogramming. To assess this ...

Ferroptosis induces significant changes in mitochondrial morphology, including membrane condensation, volume reduction, cristae alteration, and outer membrane rupture, affecting mitochondrial function ...

Five major protein import pathways have been identified so far: (1) Presequence-carrying preproteins are imported through the translocase of the outer mitochondrial membrane (TOM) and the translocase ...

In a new study, scientists at Umeå University have found a way to break open the protective walls of pollen grains—one of the ...

recent studies of mitochondrial transfer and development of therapeutic approaches, including cell engineering and clinical trials for children requiring extracorporeal membrane oxygenation. The ...

recent studies of mitochondrial transfer and development of therapeutic approaches, including cell engineering and clinical trials for children requiring extracorporeal membrane oxygenation.

Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how mitochondria influence the body's immune response through modulating specific cell signaling ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...