Recent breakthroughs in understanding the prostaglandin D2 (PGD2) receptor 1 (DP1) are paving the way for innovative ...

Kinases differ in this respect from other large gene families, such as G protein-coupled receptors, which interact in their druggable site with a wide range of structurally diverse ligands ...

Agency supports primary and novel secondary and exploratory endpoints proposed for Phase 3 Trial(s) Opportunity to utilize ...

Peptidomimetics are synthetic analogs that retain the essential structure and function of peptides but with chemical ...

Taste, pain, or response to stress—nearly all essential functions in the human body are regulated by molecular switches ...

Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States ...

Limited data exist on the association of glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) with the risk of venous thromboembolism. This meta‐analysis aimed to investigate the association between ...

This review delineates the intricate roles of Toll-like receptors (TLRs), essential components of the innate immune system, in mediating host responses during sepsis. TLRs recognize ...

Biosplice stands at the forefront of research concentrating on the study and regulation of Cdc2-like kinases (CLKs) and dual-specificity tyrosine-regulated kinases (DYRKs). These kinases play pivotal ...