News

New Scientist6h
We’re getting close to recreating the first step in evolution of life
Life is thought to have begun when RNA began replicating itself, and researchers have got close to achieving this in the lab ...
C&EN2d
1,4-Addition Ugi Reaction Using Cyclic α,β-Unsaturated Ketone as Substrate
† China International Science and Technology Cooperation Base of Food Nutrition/Safety and Medicinal Chemistry, Sino-French Joint Lab of Food Nutrition/Safety and Medicinal Chemistry, Key Laboratory ...
IEEE2d
Enhancement of Diffraction Efficiency Based on the Addition Principle of Coded Digital Gratings
Based on the proposed addition principle, the coded metagratings can adjust the scattering angle flexibly. This method overcomes the limitation that traditional grating can only obtain discrete ...
C&EN4d
In Situ Recycling of Chiral Ligand and Surplus Nucleophile for a Noncatalytic Reaction: Amplification of Process Throughput in the Asymmetric Addition Step of Efavirenz (DMP 266)
Chemical Process R&D Department, Process Research Facility, The DuPont Pharmaceuticals Company, ‡ Deepwater, New Jersey 08023-0999, U.S.A. Article Views are the COUNTER-compliant sum of full text ...
eLife6d
Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape
Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).