TSB normally binds to and activates another enzyme, TSA (tryptophan synthase alpha subunit). This leads to the brief formation of indole, which is then immediately converted to tryptophan by TSB.

They saw how the enzyme changed at different acidity levels, revealing its activation process. They discovered that metacaspase 9 only becomes active in acidic environments —between pH 4.6 and 5.6.

Natural enzyme capable of cleaving cellulose could transform biofuel production by José Tadeu Arantes, FAPESP Editors' notes ...

For organs to develop, grow and regenerate, cells must proliferate. But when that process goes awry, leading to uncontrolled cell growth, cancer can emerge. New CU Boulder research, published in the ...

A U.K. startup, originating from founder Jacob Nathan’s high school science project on using enzymes to break down plastic waste, has secured an oversubscribed $18.3 million in Series A funding ...

Having found an enzyme, AetD, involved in that pathway that synthesizes a nitrile group—which is uncommon in nature—Moore’s team went on to examine public datasets for related enzymes (Nat ...

Enzymes, meanwhile, are superstars of stereoselectivity—but there’s only one enzyme that naturally works with fluorinated substrates. Fortunately, it’s possible to teach old enzymes new tricks.

Earth’s immense web of life fill three broad domains—archaea, bacteria, and eukarya. Scientists from Monash University recently discovered hydrogen-producing enzymes in archaea, which were ...

Like RuBisCO, this enzyme is an important part of photosynthesis in plants. In nature, PRK produces a chemical that RuBisCO needs to do its job — capturing carbon and turning it into food.

As enzymes are involved at every stage of cell regulation, a better understanding of their role and function allows them to be exploited in the clinic, both as diagnostic and therapeutic agents.