AIRNA’s lead candidate AIR-001 works by correcting the most common pathologic mutation driving the rare disease alpha-1 ...

BioVersys highlighted the urgent need for safe treatments for CRAB infections, which can have death rates in hospitals as ...

Primrose Bio announced a new product to improve the manufacturing on long-template mRNA vaccines. 1 The Prima RNApols ExTend ...

R&D Expenses: Research and development expenses for the year ended December 31, 2024 decreased to approximately $2,044,000 ...

The RNA polymerase is responsible for the replication of viral genetic material and the activation of viral genes, and is essential for the replication of the virus in cells. It is therefore a ...

Replicative polymerase from NrS-1 phage (NrSPol) is a representative of the PrimPols. In this study, we identified key residues for the catalytic activity of NrSPol and found that a loop in NrSPol ...

Global Enzymes Market is valued approximately at USD 12.1 billion in 2022 and is anticipated to grow with a healthy growth rate of more than 6.80% over the forecast period 2024-2032. Read the Market ...

In (+)-stranded RNA viruses ... of nucleotide incorporation. Polymerase residues that change conformation upon dNTP binding include an extended loop in HIV-1 RT 17. In contrast, residues altering ...

Here we present an improved single-cell genome amplification method called Improved Single-cell Genome Amplification (iSGA) by phi29 DNA polymerase modification and enzyme reaction system optimization ...

The Positive Transcription Elongation Factor b (P-TEFb) phosphorylates Ser2 residues of the C-terminal domain (CTD) of the largest subunit (RPB1) of RNA polymerase II and is ... the behavior of ...

Errors during transcription may play an important role in determining cellular phenotypes: the RNA polymerase error rate is >4 orders of magnitude higher than that of ...