Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level.

Amyotrophic lateral sclerosis (ALS) is a disease that destroys the nerves necessary for movement. About 30,000 people in the ...

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization ...

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

The RNA cloud formed around genes regulates their readout into RNA. Triplexes help define where in the genome a cloud forms. Proteins and other fl ...

Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

"By imaging the whole transcriptome at the individual transcript level and advancing sensitivity across any in situ RNA assay, these developments in CosMx represent a historic milestone in the study ...

A scientific revolution is underway as researchers push to bring atomic-level precision, once reserved for small molecule ...

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

Letter, Bloomberg Distinguished Professor Jeff Coller discussed his research on the development of a new experimental protein ...