News

C&EN9d
Dopant-Induced Charge Redistribution on the 3D Sponge-like Hierarchical Structure of Quaternary Metal Phosphides Nanosheet Arrays Derived from Metal–Organic Frameworks for ...
Faculty of Materials Science and Technology, University of Science, Ho Chi Minh City 700000, Viet Nam Center for Innovative Materials and Architectures, Ho Chi Minh City 700000, Viet Nam Vietnam ...
The EMBO Journal12d
Crystal structure of ATF‐2/c‐Jun and IRF‐3 bound to the interferon‐β enhancer
Transcriptional activation of the interferon‐β (IFN‐β) gene requires assembly of an enhanceosome containing the transcription factors ATF‐2/c‐Jun ... of 24 bp. The structure, together with in vitro ...
C&EN14d
Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors
Division of Anti-tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China University of ...
eLife22d
Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein
Comparing the spike protein binding reactivity, angiotensin-converting enzyme-2-blocking, and in vitro SARS-CoV-2 virus ... Native-PAGE analysis revealed that the antibodies comprised three quaternary ...
The Lancet24d
Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
bCenter for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA cDepartment of Pediatrics and the Herman B Wells Center for Pediatric Research, Indiana ...
BioSpace24d
Innovent Announces Oral Presentation of Full Phase 2 Clinical Data for Efdamrofusp Alfa (IBI302), First-in-class anti-VEGF/complement Bispecific Fusion Protein at ARVO 2025
The data were from the Phase 2 clinical study of high-dose IBI302 (NCT05403749 ... IBI302 is a recombinant fully human bispecific fusion protein of Innovent Biologics with global proprietary rights.