However, little is known about how ICAM-1 is up-regulated in human airway epithelial cells. In this study, we show that tumor TNF-α induces monocyte adhesion to A549 human lung airway epithelium ...

the part of the study where the engineered lung mesenchymal cells are combined with lung epithelial cells in culture dishes (so called "recombinants") is particularly exciting as this resulted in ...

1,2 The outcome of an acute lower respiratory tract infection depends on the virulence of the organism and the inflammatory response in the lung ... and epithelial cells. Many plasma proteins ...

While the use of in vitro (outside the body) models generated from primary pulmonary epithelial cells that mimic the human airways has increased in popularity over recent years, their availability ...

Researchers have shown that the oncogene-encoded molecule Src is responsible for epithelial ... lung and pancreatic cancer and this work provides mechanistic insight into its roles in cancer cell ...

Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease of lung parenchymal scarring that is triggered by ...

In a Scientific Reports study, University of Alabama at Birmingham researchers show how a low dose of cadmium produces a deleterious stress in lung epithelial cells, and their findings highlight ...

“Epithelial cells in the lung are typically envisioned as supporting respiratory functions, while MHC-II is understood to connect immune cells to immune cells, so the finding that MHC-II on lung ...

The concept that IPF is associated with aberrant epithelial cell types is consistent with a recent clonogenic analysis of chronic obstructive pulmonary disease (COPD) conducted by Xian and McKeon.

Alveolar epithelial type 1 cells, which line lung tissues, are crucial to the exchange of oxygen and carbon dioxide gases. And alveolar type 2 cells or (AT2s) are known to act as stem cells to ...

Rhinovirus infects airway epithelial cells, indicating that viral infection ... 21 In contrast to the sterile airways of a healthy lung, in stable COPD, the presence of respiratory pathogens ...