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TCM Group, Cavendish Laboratory, University of Cambridge, Madingley Road, Cambridge CB3 0HE, United Kingdom, Computational Biomolecular Dynamics Group, Max-Planck-Institute for Biophysical Chemistry, ...
The authors investigate the influence of local dynamics and allosteric regulation on guide RNA binding affinity and DNA cleavage specificity through molecular dynamics simulations, advanced NMR ...
Contributed by G. Marius Clore; received March 20, 2025; accepted April 15, 2025; reviewed by Lewis E. Kay and Peter E. Wright ...
Contribution from the Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, MRM Corporation, Savoy, 101 Tomaras Avenue, Savoy, ...