¹H-NMR chemical shifts typically range from 0 to 14 ppm ... With the quantity of each proton type established, the chemical shift positions of the signals are assessed to determine their ...

The effects of temperature and NaCl on the micellization of CHAPS, a zwitterionic detergent widely used in membrane protein studies, have been investigated by NMR spectroscopy. We found that the two ...

TCM Group, Cavendish Laboratory, University of Cambridge, Madingley Road, Cambridge CB3 0HE, United Kingdom, Computational Biomolecular Dynamics Group, Max-Planck-Institute for Biophysical Chemistry, ...

The authors investigate the influence of local dynamics and allosteric regulation on guide RNA binding affinity and DNA cleavage specificity through molecular dynamics simulations, advanced NMR ...

Biochemical and NMR protein-protein interaction profiling along with cellular transcription studies indicate that the RXR ligand set, which lacks selective Nur77-RXRγ agonists, may influence ...

Contributed by G. Marius Clore; received March 20, 2025; accepted April 15, 2025; reviewed by Lewis E. Kay and Peter E. Wright ...