A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, according to new research.

New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins ...

Array Bridge is testing promising drug candidates that can effectively bind and even degrade target proteins, but not via their active sites.

Protein structure predictions are bioinformatic analyses that produce predicted protein structures automatically using the protein amino acid sequence ... metal binding sites in proteins.

The Human Domainome 1—the largest library of human protein variants—reveals the cause of certain genetic disorders, paving ...

When exposed to antibiotics, approximately one out of every 10 8 -10 9 bacteria develops resistance due to spontaneous ...

Proteins change their conformations as part of their biological functions, for example, when binding another molecule (ligand). Two pathways are conceivable: Either the ligand binds preferentially to ...

For the first time, scientists have identified promising drug candidates that bind irreversibly with a notoriously undruggable cancer protein target ... inserted binding sites for cJun into ...

Although deep learning models have been widely used to capture the syntactic structure, word semantics, or semantic meanings of polypeptide and protein sequences ... predict PepPIs and identify ...

allowing metal ions to enter a metal binding site inside the protein. Then, this metal binding site will face inward, releasing the metal into the cytoplasm. In a first-of-its-kind discovery ...

A research team has uncovered new insights into the molecular mechanisms of ADAR1, a protein that ... depends on RNA sequence, duplex length and mismatches near the editing site.