In a new move, researchers have shown that protein design software can incorporate motion into its outputs. The resulting ...

"We rely solely on initial protein sequences and ligand SMILES strings ... with its ligand without the need for predefined binding site information," Hy said. "This streamlined approach ...

The scientists next hybridize the DNA to a microarray containing sequences from an organism’s genome ... allowing a more precise mapping of protein-DNA binding sites. Exploring ChIP combined with NGS, ...

Yet natural protein binding sites often occur within a three-dimensional ... The tool predicted 56 β-barrel structure sequences that could potentially bind a molecule called DFHBI, which ...

giving researchers a fast and easy way to identify key protein-binding areas. One finding showed that mutations can occur within the chromatin sequence, thereby creating a new and accessible site ...

Stanton and Kolatkar teamed up with colleagues in Singapore to determine how transcription factor proteins assemble ... Interestingly, the binding sequences differed subtly for the two ...

Diazoxide is bound at one major binding site on human albumin. The association constant for this site is 1.7 × 10 4 liters per mole at 37°C. At usual therapeutic concentrations diazoxide is ...