Researchers have developed an AI system capable of predicting whether and why proteins form sticky clumps, a process ...

Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, ...

Prions, mysterious shape-shifting proteins, can lead to brain disorders such as Creutzfeldt-Jakob disease in humans and ...

Familial prion diseases are due to dominantly inherited, germline mutations in the PRNP gene that encodes the prion protein (PrP). The cellular mechanism underlying the pathogenic effect of these ...