Prions, mysterious shape-shifting proteins, can lead to brain disorders such as Creutzfeldt-Jakob disease in humans and ...

We decided not to change the two amino acids, proline and glycine, because they help to maintain the structure of the protein. Then we tested these different versions (mutants) of the prion protein to ...

Contribution from the Dipartimento di Chimica, Università di Firenze, Via della Lastruccia 3, I-50019 Sesto Fiorentino, Italy, European Laboratory for Nonlinear Spectroscopy (LENS), Via Nello Carrara ...

Prion-like proteins can propagate across species, potentially contributing to disease. Here the gut microbiome was analyzed ...

A fter silently lurking for almost 50 years, a prion disease erupted in the brain of a woman in the US, triggering a rapid ...

Disease-associated prion protein (PrP Sc) accumulates in FDCs (ref. 6), which function as antibody- and complement-dependent antigen traps. Here we investigated whether the mechanisms by which ...

Researchers have developed an AI system capable of predicting whether and why proteins form sticky clumps, a process ...

Researchers have captured a time-resolved video of a protein interaction essential to healthy brain development.

To create catalysts that built cyclopropanes with an enantiomeric ratio of 99:1, they had to study the structure of their protein catalysts and make adjustments based on their chemical knowledge.