Platelet activation is a complex and dynamic process, involving the co-ordination of numerous receptors to initiate shape change and aggregation. Under pathological conditions, alterations in the ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

The platelet TLR4 is one important pattern recognition receptor and binds to lipopolysaccharides from Gram-negative bacteria. Studies using an animal model for bacterial sepsis revealed that TLR4 ...

Megakaryocytes (MKs), known for their role in platelet production ... The review emphasizes the expression of immune receptors by MKs, such as toll-like receptors (TLRs), Fc gamma receptors ...

Megakaryocytes (MKs), known for their role in platelet production ... The review emphasizes the expression of immune receptors by MKs, such as toll-like receptors (TLRs), Fc gamma receptors ...

Eledon Pharmaceuticals has a promising anti-CD40L antibody for organ rejection prevention in transplantation. Learn more ...

DCI was adjudicated by three independent clinicals. Blood was used from 148 aSAH patients (n=101 no DCI, N=47 DCI) for analysis of TEG, platelet receptors for activation (CD62p) and aggregation (PAC-1 ...

Glucagon-like peptide-1 receptor agonist (GLP-1 RA) medications for weight loss are significantly transforming the fiel ...

Molecular communications in the bloodstream is a promising area of research, since the bloodstream has the ability to ...