Cryopreserved platelets may reduce bleeding in patients with thrombocytopenia. Researchers sought to determine the predictive value of mean platelet volume as a marker for cancer outcomes.

Angiogenesis is defined as the formation of new blood vessels ... For example, the endothelial cells that are activated by VEGF may secrete platelet derived growth factor. PDGF, in turn, bind to ...

In addition, endothelial PGE2, PMPs and extracellular vesicles can also enhance platelet activation and induce thrombosis and thrombo-inflammation in growing tumors. After reaching a certain size, ...

Angiogenesis is a complex process in which the original endothelial ... (GM-CSF)/granulocyte colony-stimulating factor (G-CSF), hepatocyte growth factor (HGF), platelet-derived growth factor (PDGF), ...

Angiogenesis involves the generation of new ... Further, activation of the platelet-derived growth factor receptor β (PDGFRβ) stimulates the attachment of pericytes along the new vessel branch ...

Selective platelet release of pro- or anti-angiogenic factors distinctly regulated angiogenesis. We hypothesised that selective release of platelet angiogenic factors could differently regulate ...

Observations have suggested that platelets not only augment the growth of primary tumors via angiogenesis but endow tumor cells physical and mechanical support to evade the immune system and ...

CTD appears to have meaningful, pleiotropic effects, not necessarily shared by other diuretics, on platelet aggregation, gene transcription, angiogenesis, and vascular permeability. CTD, the most ...

Platelets help to maintain blood circulation ... and nonsteady states and accounts for much of the role of platelets in angiogenesis and maintenance of vascular integrity. 20 A global ...

Results: During cycles 1 and 2 of treatment with CG+SU5416, a significant cycle-dependent activation of both the coagulation cascade and endothelial cells occurred, whereas platelet counts decreased.