Find more information on the Altmetric Attention Score and how the score is calculated. Histo-aspartic protease (HAP) from Plasmodium falciparum is a promising target for the development of novel ...

A promising new malaria drug target has been identified in a family of proteins in a malaria-causing parasite.

We have previously used phosphonic analogues to probe the structure and mechanism of inhibition for both PfA-M1 and -M17. (15) We knew the phosphonic acid would chelate the zinc ion(s), allowing us to ...