Genmab says choosing to insource cell-line development helped them to improve the antibody titers they were achieving.

Bacterial genetics is the study of the mechanisms of heritable information in bacteria, their chromosomes, plasmids, transposons and phages. Techniques that have enabled this discipline are ...

It is now clear that in most instances, resistance to multiple antimicrobial agents in the staphylococci is driven by the acquisition of discrete genetic 'accessory' elements comprising plasmids ...

Non-viral reprogramming methods include integrative strategies using transposons, non-integrative episomal and minicircle plasmids, and strategies without transgene delivery at all: protein delivery ...

Graphical Abstract. The graphical abstract displays how integron-aided AMRs to humans: Transposons capture integron gene cassettes to yield high mobility integrons that target res sites of plasmids.

(Jumping genes—also known as transposons—can benefit a species by generating genetic diversity). The lab recognized that several features of CASTs (CRISPR-associated transposases) made them ...

† Resistance genes could only be identified in 13 clones. ‡ Library from [22] used. § Phage metagenomic library. ¶ Two of three resistant clones were assumed to be from the same region due ...

The dissemination of transferable plasmids, a major type of mobile genetic elements (MGEs), is one main driver of antibiotic resistance outbreaks. While the plasmid persistence condition in well-mixed ...

Aldevron is a premier manufacturing partner, producing high-quality plasmid DNA, RNA, proteins, and other key components for the development of vaccines, gene and cell therapies, immunotherapies, and ...