Drugs designed to eliminate plaques made of beta-amyloid have a fatal problem: they need to enter the brain and remove the plaques without attacking healthy brain cells. New research from the ...

Less understood is precisely how, mechanistically, amyloid-β contributes to plaque formation. Further, while there has been much research into what genes might influence whether or not someone ...

The resulting excess of peptides aggregate together in plaques. Beta-amyloid plaques then lead to death of neurons and dementia. Researchers have known that microglia cells in the brain ...

Specifically, increases in longevity of between 10 and 18.6% and decreases in the proteotoxic effect of plaques of between 30 and 40% were observed. The studies, which form part of ángeles Morón ...

Losing the activity of a key ion channel in the brain may contribute to the buildup of a devastating and toxic protein responsible for the clumps of plaque that accumulate in Alzheimer's disease ...