Excessive sequestration of KEAP1 into phase-separated p62 bodies under conditions of impaired autophagy drives persistent ...

Rocket Pharmaceuticals acknowledged the death of a patient in a pivotal trial assessing its Danon disease gene therapy candidate RP-A501, a study that the FDA has placed on clinical hold.

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

The liposarcoma pipeline report provides detailed profiles of pipeline assets, a comparative analysis of clinical and non-clinical stage liposarcoma drugs, inactive and dormant assets, a comprehensive ...

A single Neanderthal gene slipped into lab mice triggered unexpected changes in their skeletons. Scientists in Japan uncovered traits echoing long-lost human cousins.

Genetic medicine reaches a major milestone with a system capable of inserting entire genes into human DNA. This breakthrough ...

Rejuran, a Korean-born injectable treatment made from salmon DNA – yes, you read that correctly – is becoming increasingly ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

Researchers have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through lice rather than ticks, and how it gained ...

Mounting evidence from genome studies indicates that, contrary to received wisdom, our species has undergone profound ...

Researchers work in a mobile Fire-Eye laboratory in Beijing in June 2020. The labs can identify coronavirus infections, as well as decipher and analyze human DNA. (Fu Tian/China News Service/Getty ...

The discovery of recombinant DNA proved that biology, not chemistry alone, could create new medicines like life-saving ...