Agilent (A) announced its PD-L1 IHC 22C3 pharmDx assay has received European IVDR certification for the use as a Companion Diagnostic to aid in ...

The 507 patients selected for this trial possessed moderate-to-high CLDN18.2 IHC staining in ≥75% of the tumor. Participants were randomized to receive either zolbetuximab plus CAPOX or CAPOX alone.

While all steps in the IHC protocol affect the quality of the staining outcome, three important factors to consider during initial optimization are primary antibody selection, antigen retrieval, and ...

For example, immunohistochemistry relies on lengthy staining protocols with repeated wash cycles. Also, although a powerful tool, antibodies are not always sensitive or specific. Similarly, PCR-based ...

Circulating MCP-1 may reflect the extent of hepatic macrophage activation. Stainings were performed on paraffin slides (2–3 μm) for F4/80 immunohistochemistry (IHC). F4/80 IHC was analyzed by counting ...

Review tips and techniques on how to get the best out of your experiments and overcome the most common technical challenges with our resident IHC/ICC specialist.