CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

Now, a new study shows that it also functions in the thymus where it protects thymocytes from deletion and promotes natural T Reg cell development and homeostasis. Together, these observations ...

Progenitors of intraepithelial T cells (IELps) migrate from the thymus to the intestines after birth where they can develop into unconventional intraepithelial lymphocytes. Here Ocon et al.

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body.