Acetyldigitoxin may decrease the cardiotoxic activities of Panitumumab. The therapeutic efficacy of Bacillus calmette-guerin substrain connaught live antigen can be decreased when used in ...

Panitumumab is a monoclonal antibody drug used to treat colorectal cancer. It works by blocking a protein called epidermal growth factor receptors (EGFR), which play an important role in cell ...

The US Food and Drug Administration (FDA) has approved sotorasib (Lumakras, Amgen Inc.) with panitumumab (Vectibix, Amgen Inc.) for the treatment of certain adult patients with metastatic ...

These patients were separated into 3 groups to receive either sotarasib at a 960 mg dose once daily plus panitumumab (53 patients), sotorasib at a dose of 240 mg daily plus panitumumab (53 ...

We randomly assigned 463 patients with 1% or more EGFR tumor cell membrane staining, measurable disease, and radiologic documentation of disease progression during or within 6 months of most recent ...

A suspicion from retrospective data has now been confirmed by a prospective clinical trial: adding panitumumab (Vectibix) to standard chemotherapy in left-sided RAS wild-type metastatic colorectal ...

Combining the KRAS G12C inhibitor sotorasib with panitumumab, an epidermal growth factor receptor (EGFR) inhibitor, may be an effective strategy. In this phase 3, multicenter, open-label ...

Panitumumab, the first fully human antibody that targets the EGFR, significantly improved the progression-free survival of patients with metastatic colorectal cancer (CRC) in a phase III trial.

NICE is unable to recommend panitumumab with 5‑fluorouracil, folinic acid and irinotecan (FOLFIRI) for previously treated metastatic colorectal cancer in adults. This is because Amgen did not provide ...