Scientists have developed SMART (silently mutate and repair template), a strategy that dramatically expands the editable ...

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists have now derived universal rules to enable the de novo design of optimal enzymes. As an example, they ...

Natural enzymes are remarkable molecular machines that enable all sorts of essential biochemical reactions. For decades, ...

In a new move, researchers have shown that protein design software can incorporate motion into its outputs. The resulting ...

"If people could design very efficient enzymes from scratch ... they found a "disorganized loop" in the structure where it was supposed to be a well-organized helix. A second round of design ...