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Nature17d
Recombinant human acid α-glucosidase enzyme therapy for infantile glycogen storage disease type II: Results of a phase I/II clinical trial
To avoid loss of glycogen, tissues were processed without en bloc staining with uranyl acetate. Semithin sections were stained with toluidine blue and thin section with uranyl acetate/lead citrate ...
Frontiers17d
NMN reverses D-galactose-induced neurodegeneration and enhances the intestinal barrier of mice by activating the Sirt1 pathway
Apoptotic activity (TUNEL, p16/p21), mitochondrial regulators (Sirt1, p-AMPK, PGC-1α), and intestinal barrier integrity (HE/AB-PAS staining) were evaluated. Sirt1 dependency was confirmed using ...