Understand why menopause causes bone density loss in women. Learn the hormonal changes responsible and effective strategies ...

Figure 3: A photomicrograph of secondary hyperparathyroidism resulting from renal insufficiency with a deep resorption cavity containing multinucleated osteoclasts. Giant cell tumor of bone is a ...

What Regional Insights Are Provided In The Report? North America was the largest region in the zoledronic acid market in 2024, with other regions covered in the report including the Asia-Pacific, ...

A second consideration is hypocalcemia—bone-modifying agents inhibit osteoclast activity and increase the risk ... 5 An additional concern with denosumab bears mention: once stopped, bone resorption ...

Background Bone resorption is a severe problem associated with inflammatory disease like periodontitis and rheumatoid arthritis. Osteoclasts, cells responsible for bone resorption, have been shown to ...

New research confirms denosumab biosimilar SB16 matches Prolia in efficacy, offering a cost-effective treatment option for ...

But this device, a low-vibration belt that resembles a fanny pack, received approval last year from the U.S. Food and Drug ...

Jan. 28, 2025 — Researchers have combined injections of a novel hydrogel with systemic osteoporosis drugs in rats, achieving rapid local increases in bone density. The results offer hope for ...

Skeletal remodeling is mediated by the integrated and tightly coupled actions of mechano-sensing osteocytes, bone-resorbing osteoclasts and bone-forming osteoblasts (Figure 1).

An increase in bone resorption markers is informative in the diagnosis of osteomyelitis in the early stages of the disease, which allows the use of this method in a comprehensive examination of ...

Bone tissue is composed of cells, namely osteoblasts, osteoclasts and osteocytes, and an extracellular matrix comprising inorganic hydroxyapatite crystals and organic collagen.