Several effective drugs that control osteoclast generation and/or function are currently available (see review in this issue by Boyle et al., page 337). Mesenchyme-derived osteoblasts rebuild the ...

Bone-destructive diseases such as osteoporosis and chronic inflammatory arthritis affect millions of people worldwide, ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering ...

Bortezomib may increase osteoblast activity but it is unclear ... agents alter abnormal bone metabolism in MM, inhibiting osteoclast function. Novel agents under evaluation, targeting the RANKL ...

Osteoblasts and osteoclasts are two types ... indicating its cytoplasmic function in osteoclast differentiation. Overall, these findings provide novel insights into the process of osteoclast ...

Although, bone remodeling by osteoblasts and osteoclasts is crucial for maintaining ... "Our study shows Gprc5a may function as a negative feedback factor for the bone formation promoting effect ...

A scale also has cells corresponding to osteoblasts and osteoclasts. Scales protect the surface of the fish body and play a role as a reservoir of calcium. With freshwater fish, the latter function is ...

Vitamin K2 inhibited osteoclastic resorption function by targeting osteoclasts ... diet-induced bone loss in obese mice through osteoblast and osteoclast activity regulation.

Osteoblasts and osteoclasts are two types ... indicating its cytoplasmic function in osteoclast differentiation. Further, ...