This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

A study by scientists at the Herbert Irving Comprehensive Cancer Center (HICCC) introduces a more cost-effective, scalable ...

Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to chromatin remodeling, a process implicated in cancer and developmental ...

April 3, 2025) Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this ...

The chip that is inserted into the 10X Genomics software, allowing researchers to analyze DNA and RNA simultaneously.

Nu.Q Discover is built on proprietary nucleosome quantification technology. It is a valuable research tool for R&D professionals working within the field of pharma epigenetics studying the ...

One chromatin remodeling mechanism called "nucleosome sliding" allows a nucleosome to be "moved" to control gene access, but how this works has been incompletely understood. To address this gap ...

One chromatin remodeling mechanism called "nucleosome sliding" allows a nucleosome to be "moved" to control gene access, but how this works has been incompletely understood. To address this gap ...

In this work, we investigate the ability of TDG to excise modified nucleobases from the simplest unit of compacted DNA, the nucleosome core particle (NCP). We measure TDG activity on a population of ...