A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

and Asp-56 are situated close enough to contact the phosphate backbone or the unpaired nucleotide base through water-mediated interactions and may contribute to maintaining a unique DNA conformation.

We introduce MADna, a sequence-dependent coarse-grained model of double-stranded DNA (dsDNA), where each nucleotide is described by three ... bonded interactions involve at most two consecutive base ...

Life is thought to have begun when RNA began replicating itself, and researchers have got close to achieving this in the lab ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

A shooting in South Los Angeles left two people dead and one woman in the hospital with serious injuries Saturday night. Police responded to reports of a shooting at Florence and Dalton avenues ...

Jesus Rodriguez led off the game with a single to extend his on-base streak to 27 straight games. In the nightcap, Brandon Leibrandt held the Sounds in check over the first three innings ...

Co-paired stars, or stars that travel together, can provide insights into processes that other stars can't. Differences in their brightness, orbits, and chemical composition can hint at different ...

A divided Supreme Court on Thursday refused to immediately reinstate a pair of independent regulators fired by the Trump administration, saying the president may have the power to summarily oust ...

Beam is a pioneer of the base-editing approach to gene-editing, which can be used to convert one nucleotide base into another without cutting both strands of DNA, unlike other technologies like ...