A study introduces a CRISPR model that predicts gRNA activity more accurately using chemically synthesized gRNAs. The model ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

The intermediate states occurring during nucleotide addition by HIV-1 RT remain unclear. Here, authors use cryo-EM to capture five unique states that show how a mobile catalytic Mg 2+ drives ...

Crystals containing two-nucleotide (nt) sticky ends (GA:TC) have been reported previously, and those crystals diffracted to 4.9 Å at beamline NSLS-I-X25. Here, we analyze the effect of varying sticky ...

As the crypto market rebounds in 2025, Lightchain AI's presale is nearing its conclusion, marking a significant milestone for early investors. With over $20.4 million raised and tokens priced at ...

While Solana marches along its expansionary trajectory, a new contender, Ruvi AI, is emerging as a key player in the blockchain space, offering groundbreaking solutions through its decentralized AI ...

We introduce MADna, a sequence-dependent coarse-grained model of double-stranded DNA (dsDNA), where each nucleotide is described by three beads localized at the sugar, at the base moiety, and at the ...

In addition, no clear-cut genetic differentiation among the allopolyploids of the Dactylorhiza majalis complex has been uncovered by investigating ITS sequences (Pillon et al., 2007) and amplified ...

John Paul DeJoria's victory over Maghreb Petroleum Exploration (MPE) and Mideast Fund for Morocco (MFM) in a federal court in the U.S. on Aug. 12 is sure to go down badly in Morocco. As Maghreb ...