The presentation will be made available the day of the event under the "Scientific Presentations” section within the Science ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

The intermediate states occurring during nucleotide addition by HIV-1 RT remain unclear. Here, authors use cryo-EM to capture five unique states that show how a mobile catalytic Mg 2+ drives ...

Trethera Corporation (“Trethera”), a clinical stage biopharmaceutical company developing first-in-class therapies for cancer ...

The potential of skin-based diagnostics using UHPLC–IMS-HRMS to offer safe, cost-effective, and field-friendly solutions for ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

Nucleotide-binding proteins are proteins that bind to nucleotides. For example, kinases bind adenosine triphosphate (ATP) and G proteins bind guanosine triphosphate (GTP). Other nucleotide-binding ...

Jacob Graham Baldwin, 27, died on Oct. 16, 2024, four days after a Saturday night altercation in Scott’s Addition. Baldwin was from Midlothian, in Chesterfield County. A grand jury has certified ...

A technique called ‘gene addition’, administered as a ‘one-time’ treatment, could be used to transform the lives of those living with previously incurable rare genetic diseases. How does ...

The predictions of these structures with regard to substrate binding are tested using equilibrium and pre-steady-state ligand binding studies, and the results confirm that a nucleotide-driven ...