Nuclear transfer of plasmid DNA complexed to an oligolysine–RGD peptide and lipofectamine appears to be an energy-dependent process involving the nuclear pore complex, since it is inhibited at 4 ...

In order for a healthy cell to function, the DNA must send manufacturing orders ... The sole portals through which these instructions pass -- nuclear pore complexes -- have a say in what the ...

The nuclear ... DNA contained in the nucleus. In spite of this barrier, there is still communication between the nucleus and the cytoplasm. This communication is regulated by the nuclear pores.

Researchers have long wondered how nuclear pores -- the all-important channels ... the cell cycle as is the question of how DNA replicates," says Martin Hetzer, Ph.D., an assistant professor ...

Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs ... enable the synthesis of DNA. Whether NPC alterations ...

“Nuclear pores” sounds like something from a skincare video. But for cell biologists, they’re a decades-long enigma. “NPCs are essential for life,” explained Dr. Francis Collins, a former director at ...

The researchers devised a method to study a large, doughnut-shaped structure called the nuclear pore complex (NPC ... most of a cell's DNA is stored in a rounded structure called the nucleus.

Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression ...

Scientists at TU Delft and the Max Planck Institute have made a new class of structurally adaptable 'mechanical' pores made from DNA that can transport molecules through cell membranes.

A new study from Sanford-Burnham Prebys Medical Discovery Institute shows that nuclear pore complexes in the nuclear membrane are vital for T cell survival. Researchers from the present study are the ...

La Jolla, CA – Researchers have long wondered how nuclear pores – the all-important channels ... the cell cycle as is the question of how DNA replicates," says Martin Hetzer, Ph.D., an ...