For example, the herpes simplex virus protein ICP27 targets ALY ... and nucleoporins with a role in RNA export Nuclear pore complexes (NPCs) are large assemblies (∼125 nm in diameter, with ...

The nuclear pore complex (NPC) mediates transport of all macromolecules between the nucleus and the cytoplasm. The structure of the NPC — a cylindrical ring-like structure lined with ...

The Shaw Prizes have been awarded annually since 2004 to recognize laureates in three areas: astronomy, mathematical sciences ...

Researchers reveal that Merkel cell polyomavirus bypasses normal nuclear entry routes by exploiting the temporary breakdown ...

Fig 1. T-cell responses against Epstein-Barr virus nuclear antigen 1 (EBNA-1), latent membrane protein 2 (LMP-2), and p54 in healthy donors. Mean frequency of antigen-specific T cells against EBNA-1 ...

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This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

CSIR-Centre for Cellular & Molecular Biology, Uppal Road, Hyderabad 500007 (AP), India. The authors are grateful to the Council of Scientific and Industrial Research (CSIR-CCMB), India, for ...

Contributed by Dinshaw J. Patel, March 16, 2021 (sent for review January 4, 2021; reviewed by Wei Yang and Hongtao Yu) Structural maintenance of chromosomes (SMC) complexes are essential for ...

This review provides a comprehensive insight into how membrane trafficking modulators such as Rab and Rab-like proteins, and the exocyst complex control transport to the primary cilia, in turn ...

The method enabled the simultaneous detection of each virus by using three sets of specific primers and probes in a single reaction mixture, exhibiting revolutionary potential for its application in ...