Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules into and out of the nucleus. This microscopic metropolis relies on an ...

The nuclear envelope, for example, is a highly regulated membrane barrier ... rupture because they are not able to diffuse back to the cytosol through the nuclear pores following nuclear membrane ...

Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a ...

UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications ...

Researchers at Kanazawa University report in Cell Reports how alterations in the nuclear pores lead to the degradation of anti-tumor proteins. Several types of cancer are believed to be linked to ...

This transport of large goods is similar to how large macromolecules are trafficked out of the cell nucleus via an export pathway termed nuclear envelope budding ... out of the nucleus by bypassing ...

One element of particular complexity is the nuclear pore complex. Surrounding the eukaryotic cell nucleus is a double membrane, the nuclear envelope, which encloses the genetic material of the cell ...

Figure 1 Representation of the nuclear envelope components and their proposed functions ... endoplasmic reticulum; NPC, nuclear pore complex; LINC, linker of nucleoskeleton and cytoskeleton complex; ...

The submarine's missiles can strike targets up to 4,000 miles away. America's main nuclear deterrent glides undetected under the oceans as it carries a cargo of ballistic missiles that will ...

That's where the NPC comes in. Hundreds - sometimes thousands - of these pores are embedded in the nuclear envelope, creating gateways that allow certain molecules to pass. The study's first ...