The organoid's response to therapy mirrored the response of the actual tumor in the patient's brain. That is, if the tumor-derived organoid shrunk after treatment, so did the patient's actual ...

Additionally, the authors highlight the influence of these techniques on organoid properties such as stemness, ...

PDO and PDXO-PDX derived tumor organoid culture. Generation of tumor organoid models ... shRNA positive control clones (GAPDH and EG5) and negative control clones (non-silencing and empty vectors) are ...