Understanding how cells transform into specialized types during human development is a central challenge in biology. This ...

Key cells in the brain, neurons, form networks by exchanging signals, enabling the brain to learn and adapt at incredible speed. Researchers of the Delft University of Technology in The Netherlands ...

Here we show that the deficit in neurogenesis reflects alterations in the microenvironment that regulates progenitor-cell fate, as well as a defect in the proliferative capacity of the neural ...

ReSonance™ (ANP1), an auditory neuronal progenitor cell therapy for the potential treatment of auditory neuropathy; (iv) PNC1, a photoreceptor neural cell therapy for the potential treatment of ...

The 3D-printed brain-like model from TU Delft promotes structured neuronal networks, offering a new tool for investigating brain disorders like Alzheimer's.

During neurogenesis, stem cells become non-specialized neural progenitor cells, which in turn produce specific kinds of neurons. The bulk of neurogenesis happens during the prenatal period of ...

After 2024, which saw a steady recovery by the life sciences industry, it looks like 2025 is set to be a year of change and ...

Single-cell transcriptome analysis of embryos in which the Shh ... It will be of great value to investigators examining early stages of neural plate patterning, neural progenitor diversity, and the ...

Introduction: Neurosphere culture is widely used to expand neural stem and progenitor cells (NSPCs) of the nervous system. Understanding the identity of NSPCs, such as the principals involved in ...

The neural tube is a pseudostratified epithelium composed of neuroepithelial cells (NECs) that are highly polarized along the apico-basal axis. This pool of progenitor cells will be amplified by ...