A precision medicine workflow integrating proteomics and personalized xenograft models was developed and applied to an ...

Thymically committed regulatory CD4 T cells (tTregs) are essential for immune homeostasis and self-tolerance. We established the human tTreg Expression Signature by comparing genome-wide ...

This important study utilizes humanized mice, in which human immune cells are introduced into immune-deficient mice, to provide convincing evidence that two helper CD4 T-cell subsets, T-follicular ...

Background: The murine model of cerebral aneurysm (CA) serves as a prevalent tool for investigating the molecular underpinnings of CA. However, the extent to which the CA murine model aligns with that ...

Hypertension and Vascular Research Unit, Lady Davis Institute for Medical Research, Quebec, Canada (O.B., P.P., E.L.S.). Hypertension and Vascular Research Unit, Lady ...