This important study utilizes humanized mice, in which human immune cells are introduced into immune-deficient mice, to provide convincing evidence that two helper CD4 T-cell subsets, T-follicular ...

This important study utilizes humanized mice, in which human immune cells are introduced into immune-deficient mice, to provide solid evidence that two helper CD4 T-cell subsets, T-follicular helper ...

IL-37 expression has been identified in diverse tissues, including lymph nodes, thymus, lung, intestine ... In a humanized allergic asthma NOD/SCID murine model, IL-38 demonstrated anti-inflammatory ...

This result suggested a higher activity for most of the “private” genes in the thymus when compared to the peripheral compartments. Altogether, we provide a unique resource to inform future studies, ...

Together, our studies underscore the critical role of Tet1/3 in the early and long-term epigenetic programming of CD8 T cells in the thymus. Most notably, they bring into focus the importance of ...

Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, 881 Madison Ave, Memphis, Tennessee 38163, United States Department of Pharmaceutical Sciences, University of ...

Objective Development of obesity and type 2 diabetes (T2D) are associated with gut microbiota (GM) changes. The gut viral community is predominated by bacteriophages (phages), which are viruses that ...