Advanced imaging technologies are uncovering surprising roles for CD8+ T cells—not just in immune defense, but also in supporting tissue repair and regeneration.

Recognition of self-peptide–MHC complexes in the thymus is necessary for thymocyte survival, but can also result in cell death. Here, the authors provide a unique insight into this apparent ...

Background Pre-clinical mouse models are invaluable tools to investigate the mechanisms driving systemic lupus erythematosus (SLE) and identify therapeutic targets to treat human disease. The BXSB.Yaa ...

T cells have been found in the brain meninges as well (May 2021 news; Feb 2025 news), but flow cytometry and single-cell RNA sequencing confirmed that these SFO CD4+ T cells are distinct. They ...

However, recent studies have identified the thymus as a novel and promising source of Tregs, overcoming the abovementioned limitations. Currently, human thymus-isolated regulatory T cells (thyTregs) ...

The mouse is rechargeable, which is welcome as it negates any need for disposable batteries, unlike the Razer Pro Click Mini ($79). As well as housing its own dongle, the MagMouse features a built ...

It was when I booted up Cyberpunk 2077 that I ran into my first problem with the mouse controls. The Nintendo Switch 2 still wants you to treat the mouse Joy-Con as a standard controller in play.

Results Expression of GPR15 and α4β7 was significantly increased on Treg rather than Teff cells in peripheral blood of patients with UC as compared with Crohn’s disease and controls. In vivo analysis ...