Thymus Treg (tTreg 6) cells constitutively express the FoxP3 marker and have an essential role in maintaining tolerance to self-antigens. 7 In contrast, peripheral Treg (pTreg 6) cells are ...

His team has previously shown that a gene called AIRE is responsible for making cells in the medulla region of the thymus produce their random handful of “self” proteins to test newborn T cells for ...

Cells from a mouse embryo were reprogrammed to look like thymus cells and then transplanted into a mouse. The cells formed a replacement organ with the same structure, complexity and function as a ...

Fully Functional Thymus Grown In Mouse Growing organs for human transplant is still a long way off, but this study is still a step forward. Mary Beth Griggs. August 25, 2014. Get our newsletter!

The thymus is the primary site of T-cell development and plays a critical role in the adaptive immune system, with athymia resulting in profound immunodeficiency. 1 The thymus is a heterogeneous ...

A new preclinical model for thymic cancer developed by Weill Cornell Medicine investigators has revealed insights into how a common mutation found in thymic epithelial tumors sparks their formation.